| month | day | visitor | score | home | score |
|---|
| November | 2, 2010 | Pacers | 75 | Timberwolves | 86 |
| November | 4, 2010 | SuperSonics | 126 | Timberwolves | 114 |
| November | 5, 2010 | Timberwolves | 91 | Grizzlies | 73 |
| November | 6, 2010 | Timberwolves | 78 | Raptors | 108 |
| November | 9, 2010 | Timberwolves | 108 | Blazers | 82 |
| November | 10, 2010 | Pelicans | 86 | Timberwolves | 90 |
| November | 16, 2010 | Suns | 80 | Timberwolves | 89 |
| November | 18, 2010 | Pistons | 72 | Timberwolves | 93 |
| November | 19, 2010 | Timberwolves | 94 | Knicks | 95 |
| November | 20, 2010 | Jazz | 87 | Timberwolves | 100 |
| November | 22, 2010 | Timberwolves | 88 | SuperSonics | 113 |
| November | 24, 2010 | Timberwolves | 84 | Mavericks | 97 |
| November | 27, 2010 | Mavericks | 66 | Timberwolves | 100 |
| November | 28, 2010 | Timberwolves | 98 | Hornets | 82 |
| November | 29, 2010 | Jazz | 92 | Timberwolves | 114 |
| December | 2, 2010 | Timberwolves | 80 | Kings | 79 |
| December | 5, 2010 | Lakers | 75 | Timberwolves | 88 |
| December | 11, 2010 | Timberwolves | 82 | Celtics | 114 |
| December | 13, 2010 | Lakers | 85 | Timberwolves | 73 |
| December | 17, 2010 | Bulls | 88 | Timberwolves | 86 |
| December | 19, 2010 | Timberwolves | 112 | Pelicans | 97 |
| December | 21, 2010 | Timberwolves | | Hornets | |
| December | 23, 2010 | Timberwolves | | Magic | |
| December | 24, 2010 | Timberwolves | | SuperSonics | |
| December | 27, 2010 | Knicks | | Timberwolves | |
| December | 29, 2010 | Timberwolves | | Mavericks | |
| December | 30, 2010 | Blazers | | Timberwolves | |
| January | 1, 2011 | 76ers | | Timberwolves | |
| January | 4, 2011 | Magic | | Timberwolves | |
| January | 6, 2011 | Timberwolves | | Raptors | |
| January | 8, 2011 | Kings | | Timberwolves | |
| January | 9, 2011 | Timberwolves | | Kings | |
| January | 11, 2011 | Timberwolves | | Nets | |
| January | 13, 2011 | Timberwolves | | Blazers | |
| January | 17, 2011 | Cavaliers | | Timberwolves | |
| January | 19, 2011 | Timberwolves | | Jazz | |
| January | 20, 2011 | Knicks | | Timberwolves | |
| January | 22, 2011 | Timberwolves | | 76ers | |
| January | 28, 2011 | Celtics | | Timberwolves | |
| January | 29, 2011 | Timberwolves | | Thunder | |
| January | 30, 2011 | Mavericks | | Timberwolves | |
| February | 2, 2011 | Jazz | | Timberwolves | |
| February | 5, 2011 | Timberwolves | | Knicks | |
| February | 6, 2011 | Timberwolves | | Wizards | |
| February | 14, 2011 | Hornets | | Timberwolves | |
| February | 15, 2011 | Timberwolves | | Suns | |
| February | 17, 2011 | Nuggets | | Timberwolves | |
| February | 19, 2011 | Nets | | Timberwolves | |
| February | 21, 2011 | Timberwolves | | Pistons | |
| February | 25, 2011 | Raptors | | Timberwolves | |
| February | 26, 2011 | Timberwolves | | Bucks | |
| February | 27, 2011 | Heat | | Timberwolves | |
| March | 2, 2011 | Timberwolves | | Nuggets | |
| March | 3, 2011 | Pacers | | Timberwolves | |
| March | 5, 2011 | Bucks | | Timberwolves | |
| March | 7, 2011 | Timberwolves | | Bulls | |
| March | 8, 2011 | Timberwolves | | Bulls | |
| March | 9, 2011 | Timberwolves | | Cavaliers | |
| March | 14, 2011 | Timberwolves | | Mavericks | |
| March | 16, 2011 | Timberwolves | | Hornets | |
| March | 19, 2011 | Wizards | | Timberwolves | |
| March | 20, 2011 | SuperSonics | | Timberwolves | |
| March | 23, 2011 | Timberwolves | | Kings | |
| March | 26, 2011 | SuperSonics | | Timberwolves | |
| March | 27, 2011 | Timberwolves | | Jazz | |
| April | 1, 2011 | Timberwolves | | Pacers | |
| April | 2, 2011 | Hornets | | Timberwolves | |
| April | 6, 2011 | Thunder | | Timberwolves | |
| April | 11, 2011 | Timberwolves | | Heat | |
| April | 12, 2011 | Timberwolves | | Blazers | |
| April | 15, 2011 | Timberwolves | | Lakers | |
| April | 16, 2011 | Grizzlies | | Timberwolves | |
| April | 18, 2011 | Knicks | | Timberwolves | |
| April | 19, 2011 | Nets | | Timberwolves | |
| April | 21, 2011 | Bulls | | Timberwolves | |
| April | 25, 2011 | Nets | | Timberwolves | |
| April | 26, 2011 | Lakers | | Timberwolves | |
| April | 28, 2011 | Pacers | | Timberwolves | |
| April | 30, 2011 | Timberwolves | | Bulls | |
| May | 1, 2011 | Timberwolves | | Raptors | |
| May | 2, 2011 | Lakers | | Timberwolves | |
| May | 3, 2011 | Timberwolves | | Lakers | |