| month | day | visitor | score | home | score |
|---|
| November | 4, 2012 | Lakers | 79 | Timberwolves | 90 |
| November | 6, 2012 | Mavericks | 97 | Lakers | 83 |
| November | 7, 2012 | 76ers | 94 | Lakers | 75 |
| November | 9, 2012 | Bulls | 81 | Lakers | 82 |
| November | 10, 2012 | Lakers | 103 | Pacers | 81 |
| November | 12, 2012 | Lakers | 84 | Pistons | 80 |
| November | 14, 2012 | Timberwolves | 67 | Lakers | 93 |
| November | 16, 2012 | Jazz | 87 | Lakers | 86 |
| November | 19, 2012 | Lakers | 93 | Wizards | 74 |
| November | 20, 2012 | Thunder | 90 | Lakers | 84 |
| November | 21, 2012 | Nuggets | 77 | Lakers | 84 |
| November | 23, 2012 | Raptors | 93 | Lakers | 83 |
| November | 25, 2012 | Lakers | 78 | Magic | 86 |
| November | 27, 2012 | Lakers | 84 | Pacers | 76 |
| November | 29, 2012 | Bucks | 105 | Lakers | 79 |
| December | 1, 2012 | Lakers | 87 | Hornets | 67 |
| December | 3, 2012 | Mavericks | 87 | Lakers | 75 |
| December | 6, 2012 | Hornets | 72 | Lakers | 82 |
| December | 7, 2012 | Lakers | 75 | Blazers | 79 |
| December | 12, 2012 | Kings | 84 | Lakers | 91 |
| December | 13, 2012 | Lakers | 105 | Bucks | 113 |
| December | 15, 2012 | Pelicans | 78 | Lakers | 82 |
| December | 17, 2012 | Raptors | 91 | Lakers | 88 |
| December | 20, 2012 | Lakers | 77 | Cavaliers | 63 |
| December | 23, 2012 | Lakers | 107 | Knicks | 109 |
| December | 25, 2012 | Lakers | 92 | Nuggets | 113 |
| January | 2, 2013 | Hornets | 73 | Lakers | 96 |
| January | 5, 2013 | Lakers | 103 | Nets | 107 |
| January | 6, 2013 | Lakers | 82 | Bulls | 98 |
| January | 8, 2013 | Lakers | 81 | Timberwolves | 108 |
| January | 11, 2013 | Pistons | 115 | Lakers | 106 |
| January | 12, 2013 | Cavaliers | 90 | Lakers | 88 |
| January | 13, 2013 | Lakers | 64 | Raptors | 102 |
| January | 14, 2013 | Heat | 92 | Lakers | 108 |
| January | 15, 2013 | Lakers | | Raptors | |
| January | 17, 2013 | Lakers | | SuperSonics | |
| January | 18, 2013 | Pacers | | Lakers | |
| January | 19, 2013 | Lakers | | Knicks | |
| January | 20, 2013 | Lakers | | Bulls | |
| January | 26, 2013 | Lakers | | Grizzlies | |
| January | 27, 2013 | Lakers | | Blazers | |
| January | 31, 2013 | Wizards | | Lakers | |
| February | 1, 2013 | Lakers | | Kings | |
| February | 2, 2013 | Hornets | | Lakers | |
| February | 4, 2013 | Blazers | | Lakers | |
| February | 7, 2013 | Magic | | Lakers | |
| February | 8, 2013 | Grizzlies | | Lakers | |
| February | 12, 2013 | Kings | | Lakers | |
| February | 13, 2013 | Lakers | | Nets | |
| February | 15, 2013 | Lakers | | Pelicans | |
| February | 16, 2013 | Kings | | Lakers | |
| February | 19, 2013 | Lakers | | Timberwolves | |
| February | 23, 2013 | Bulls | | Lakers | |
| February | 27, 2013 | Jazz | | Lakers | |
| March | 1, 2013 | SuperSonics | | Lakers | |
| March | 2, 2013 | Blazers | | Lakers | |
| March | 3, 2013 | Raptors | | Lakers | |
| March | 4, 2013 | Nets | | Lakers | |
| March | 5, 2013 | Knicks | | Lakers | |
| March | 6, 2013 | Suns | | Lakers | |
| March | 10, 2013 | Lakers | | Jazz | |
| March | 11, 2013 | Celtics | | Lakers | |
| March | 12, 2013 | Lakers | | Thunder | |
| March | 14, 2013 | Lakers | | Jazz | |
| March | 15, 2013 | Lakers | | 76ers | |
| March | 16, 2013 | Lakers | | Timberwolves | |
| March | 17, 2013 | Bulls | | Lakers | |
| March | 18, 2013 | Timberwolves | | Lakers | |
| March | 20, 2013 | Lakers | | Hornets | |
| March | 21, 2013 | Lakers | | Celtics | |
| March | 25, 2013 | Lakers | | Kings | |
| April | 4, 2013 | Pacers | | Lakers | |
| April | 6, 2013 | Mavericks | | Lakers | |
| April | 10, 2013 | Lakers | | SuperSonics | |
| April | 17, 2013 | Lakers | | Heat | |
| April | 18, 2013 | Lakers | | Suns | |
| April | 20, 2013 | Nets | | Lakers | |
| April | 21, 2013 | Lakers | | Blazers | |
| April | 22, 2013 | Blazers | | Lakers | |
| April | 24, 2013 | Lakers | | Nets | |
| April | 28, 2013 | Lakers | | Pacers | |
| April | 29, 2013 | Lakers | | Mavericks | |