| month | day | visitor | score | home | score |
|---|
| November | 5, 2011 | Knicks | 96 | Grizzlies | 120 |
| November | 6, 2011 | Pistons | 99 | Grizzlies | 111 |
| November | 9, 2011 | Magic | 70 | Grizzlies | 105 |
| November | 10, 2011 | Cavaliers | 97 | Grizzlies | 106 |
| November | 14, 2011 | Cavaliers | 100 | Grizzlies | 121 |
| November | 16, 2011 | Pelicans | 96 | Grizzlies | 111 |
| November | 17, 2011 | Suns | 110 | Grizzlies | 87 |
| November | 18, 2011 | Grizzlies | 111 | 76ers | 119 |
| November | 19, 2011 | Wizards | 100 | Grizzlies | 102 |
| November | 20, 2011 | Grizzlies | 80 | Lakers | 103 |
| November | 23, 2011 | Grizzlies | 88 | Celtics | 101 |
| November | 26, 2011 | Heat | 93 | Grizzlies | 113 |
| November | 28, 2011 | Grizzlies | 105 | Pistons | 94 |
| November | 29, 2011 | Wizards | 104 | Grizzlies | 90 |
| December | 1, 2011 | Bulls | 98 | Grizzlies | 102 |
| December | 2, 2011 | Grizzlies | 109 | Bucks | 123 |
| December | 6, 2011 | Pelicans | 107 | Grizzlies | 92 |
| December | 8, 2011 | Grizzlies | 109 | Nets | 104 |
| December | 9, 2011 | Grizzlies | 104 | Heat | 97 |
| December | 10, 2011 | Grizzlies | 81 | Thunder | 104 |
| December | 11, 2011 | Grizzlies | 102 | Magic | 84 |
| December | 14, 2011 | Grizzlies | 85 | Thunder | 97 |
| December | 16, 2011 | Magic | 71 | Grizzlies | 86 |
| December | 17, 2011 | Grizzlies | 108 | Knicks | 96 |
| December | 22, 2011 | Grizzlies | | Celtics | |
| December | 23, 2011 | Mavericks | | Grizzlies | |
| December | 24, 2011 | Heat | | Grizzlies | |
| December | 31, 2011 | Grizzlies | | Thunder | |
| January | 2, 2012 | Heat | | Grizzlies | |
| January | 3, 2012 | Wizards | | Grizzlies | |
| January | 6, 2012 | Grizzlies | | Nuggets | |
| January | 7, 2012 | Nets | | Grizzlies | |
| January | 10, 2012 | Bucks | | Grizzlies | |
| January | 11, 2012 | Grizzlies | | Bucks | |
| January | 12, 2012 | Pacers | | Grizzlies | |
| January | 15, 2012 | Grizzlies | | Heat | |
| January | 17, 2012 | Grizzlies | | Blazers | |
| January | 20, 2012 | Pistons | | Grizzlies | |
| January | 23, 2012 | Grizzlies | | Cavaliers | |
| January | 25, 2012 | Pelicans | | Grizzlies | |
| February | 1, 2012 | Jazz | | Grizzlies | |
| February | 4, 2012 | Bucks | | Grizzlies | |
| February | 5, 2012 | Suns | | Grizzlies | |
| February | 6, 2012 | Grizzlies | | Suns | |
| February | 7, 2012 | Timberwolves | | Grizzlies | |
| February | 8, 2012 | Kings | | Grizzlies | |
| February | 18, 2012 | Grizzlies | | 76ers | |
| February | 19, 2012 | Nuggets | | Grizzlies | |
| February | 21, 2012 | Grizzlies | | Raptors | |
| February | 22, 2012 | Grizzlies | | Pelicans | |
| February | 23, 2012 | Grizzlies | | Cavaliers | |
| February | 25, 2012 | Celtics | | Grizzlies | |
| February | 26, 2012 | Grizzlies | | Hornets | |
| March | 1, 2012 | Blazers | | Grizzlies | |
| March | 2, 2012 | Grizzlies | | Bulls | |
| March | 4, 2012 | SuperSonics | | Grizzlies | |
| March | 5, 2012 | 76ers | | Grizzlies | |
| March | 6, 2012 | Grizzlies | | Kings | |
| March | 7, 2012 | Nuggets | | Grizzlies | |
| March | 9, 2012 | Grizzlies | | Magic | |
| March | 10, 2012 | Grizzlies | | SuperSonics | |
| March | 11, 2012 | Celtics | | Grizzlies | |
| March | 15, 2012 | Grizzlies | | Mavericks | |
| March | 16, 2012 | Grizzlies | | Suns | |
| March | 18, 2012 | Grizzlies | | Suns | |
| March | 19, 2012 | Hornets | | Grizzlies | |
| March | 23, 2012 | Grizzlies | | Pacers | |
| March | 24, 2012 | Nuggets | | Grizzlies | |
| March | 25, 2012 | Grizzlies | | Jazz | |
| March | 27, 2012 | Thunder | | Grizzlies | |
| March | 28, 2012 | Lakers | | Grizzlies | |
| March | 29, 2012 | Grizzlies | | Celtics | |
| April | 1, 2012 | Grizzlies | | Wizards | |
| April | 5, 2012 | Pistons | | Grizzlies | |
| April | 6, 2012 | Grizzlies | | Cavaliers | |
| April | 7, 2012 | Thunder | | Grizzlies | |
| April | 8, 2012 | Raptors | | Grizzlies | |
| April | 11, 2012 | Grizzlies | | Magic | |
| April | 16, 2012 | Grizzlies | | Bucks | |
| April | 19, 2012 | Grizzlies | | 76ers | |
| April | 27, 2012 | Grizzlies | | Timberwolves | |
| May | 1, 2012 | Grizzlies | | Nuggets | |